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KMID : 0385019940100010025
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Korean Journal of Laboratory Animal Science
1994 Volume.10 No. 1 p.25 ~ p.31
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Chromosome Dissociation and Histological Study of Testis in the Sterile Male ICR Mouse
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Abstract
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Meiotic chromosomes analysis and histolagical observation of the sterile male ICR mouse were investigated by the air-drying method and the hematoxylin-eosin stain in order to compare with normal.
The frequencies of X and Y chromosome dissociation in the primary spermatocytes of normal ICR and BALE/c mice were about 7.45% and 7.33%, respectively. In the sterile ICR mouse, 24.11% of spermatocytes had unpaired X and Y chromosomes at diakinesis/metaphase I. Histological examination in the testis of sterile ICR mouse shawed an apparent block in the spermatogenesis associated with a thickening of the basal lamina and its boundary tissue and a appearance of few cells (spermatogonia and spermatocytes) in the seminiferous tubules.
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